RESEARCHERS have replicated the body’s blood-producing system by creating a bone marrow model made entirely from reprogrammed human cells.

Chronic myeloid leukemia (CML) is a hematopoietic malignancy characterized by BCR-ABL1 gene fusion. The immune microenvironment, implicated in relapse and drug resistance, poses significant challenges ...

Bone marrow adipocytes (BMAds) are situated within the bone microenvironment, in close proximity to bone cells, vascular structures, and hematopoietic tissues. The shift of bone marrow stromal/stem ...

Immune cells in the bone marrow microenvironment of AML patients are key in distinguishing a response to immunotherapy. A team of researchers from Colombia Engineering and Irving Institute for Cancer ...

Bone marrow-derived mesenchymal stem cells (BM-MSCs) represent an interesting alternative to liver or hepatocyte transplantation to treat liver injuries. Many studies have reported that MSCs can treat ...

In a recently published study, researchers at Fox Chase Cancer Center revealed for the first time that cancer cells can evade anti-cancer drugs by entering and surviving within bone marrow fibroblasts ...

Mar. 23 -- FRIDAY, June 15 (HealthDay News) -- Defects in bone marrow can lead to abnormal blood cells that cause precancerous blood diseases in mice, two new studies find. Blood cells are produced in ...

Findings from the Garvan Institute of Medical Research and Pharmaxis, an Australian pharmaceutical research company, indicate that a new treatment for bone marrow cancer myelofibrosis currently in ...

Breast cancers frequently spread to the bone, establishing tumors that are largely impervious to treatment and are associated with poor patient prognoses. A deficiency in the oxygen-carrying capacity ...