They seal epithelial cells and, under certain conditions, allow the passage of ions and water: Tight junctions form a paracellular barrier in tissues and their dysfunction is associated with diseases.
Our bodies and organs are shielded from the external environment by tissue barriers like the skin. These barriers must be tightly sealed to prevent unwanted substances from entering. This sealing is ...
Clinicopathologic features and impact of metastasectomy in patients with BRAF-mutant metastatic colorectal cancer.
Cell-to-cell junctions were visualized by ZO1-GFP, and the dynamics of cell junctions were captured by movies. When the cells indicated by * were spontaneously stretched, a continuous belt of cell ...
Barriers between stem cells play a crucial role in human development—and offer a new potential route for fertility treatment SAN FRANCISCO, CA—As a human embryo grows, a set of molecules directs cells ...
Researchers have identified a previously unknown mechanism by which the kidney precisely controls calcium excretion. The claudin-14 protein plays a key role in this process: It displaces the ...
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