Scientific research in areas such as drug development and the food industry requires rigorous testing of new chemical compounds to determine their safety for the open market and human use. One vital ...

Nickel-induced oxidative stress arises when nickel ions catalyse the formation of reactive oxygen species, overwhelming cellular antioxidant defences and resulting in peroxidation of lipids, oxidation ...

In a recent study published in Addiction Biology, authors explored the mechanisms of cannabinoid-induced mitochondrial stress, micronuclear formation, and genotoxic damage and their implications for ...

Genotoxicity assessment in mammalian systems encompasses a suite of in vitro and in vivo assays designed to detect DNA damage, gene mutations and chromosomal aberrations induced by chemical and ...

Identifying the toxicity profile of a compound is a necessity across industries and the various stages of drug development. Early stage mechanism-based in vitro assays can not only speed up the ...

Identifying and verifying low frequencies of genomic alterations resulting from off-target editing, gRNA synthesis errors, cross-contamination, or other unintended gRNA activity is critical to ...

Cannabis use causes cellular damage that increases the risk of highly cancerous tumours, according to a new paper published in the scientific journal Addiction Biology. The paper describes cannabis as ...

With industry spinning that glyphosate is harmful to health, if at all, only with co-formulants like tallowamine, the World Health Organisation's cancer agency IARC has just released a Q&A document ...

SAN FRANCISCO and TORONTO, April 01, 2021 (GLOBE NEWSWIRE) -- Claritas Pharmaceuticals, Inc. (formerly Kalytera Therapeutics, Inc.) (TSX VENTURE: KLY and OTC: KALTF) (the "Company" or "Claritas") ...

A team of researchers from the Eichman lab and associated with the Evolutionary Studies Initiative led a project that was recently published in mBio. Graduate student Noah Bradley and undergraduate ...