Per- and polyfluoroalkyl substances (PFAS), manmade chemicals that accumulate in the body over time, have been linked to liver disease and cancer, but it is not yet clear how they cause damage.

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

Doctors in China have become the first to report details about a transplant of a genetically modified pig liver into a human. The liver was transplanted last year into a person who was brain-dead, and ...

Scientists from Cincinnati Children’s Hospital Medical Center and their collaborators have used human stem cells to develop liver organoids that faithfully replicate key zones observed in human livers ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient diagnosed with brain death. During a 10-day observation period, the porcine liver ...

(A) Distinct phases of APAP-ALF. (B) Integrative multimodal approaches, including single-nucleus RNA sequencing spatial transcriptomics, four-dimensional intravital imaging and lineage tracing in both ...

Maintaining optimal liver health is essential for overall well-being, as this vital organ manages energy production, aids ...

The central vein (CV) region, driven by the Wnt signaling pathway, and the portal vein (PV) region, driven by the Notch signaling pathway, enable us to construct a biomimetic liver lobule ...

Nearly 4 in 10 Indians may have fatty liver disease, which translates to 564 million people. Fatty liver disease cases have ...

A world-first transplant in China has demonstrated that multiple gene-edited pig organs can function together inside a human body, marking a major step forward for transplant medicine.