New research reveals how tiny electrical gates in the brain, known as NMDA receptors, control learning, memory, and neuron ...

BUFFALO, N.Y. – The ability to accurately detect heat and pain is critical to human survival, but scientists have struggled to understand on a molecular level exactly how our bodies sense these ...

The lower body domain is composed of residues 56–74, 93–104, 188–207, 254–281 and 320–330 (zfP2X4 numbering) and is characterized by a β-sandwich motif formed by six β-sheets (Figure 2A and 2H).

Teasing apart the complex circuitry of the brain might someday proceed with the flip of a switch, now that scientists have invented a light-responsive version of a common class of cell-surface ...

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor ...

The process of expressing a wide variety of voltage-gated and ligand-gated ion channels enables nociceptors to transduce receptor potential into single action potentials or multiple action potentials.

Ion channels make good drug targets—they reside on the cell surface and are fast switching mechanisms. They act like cell transistors, controlling many cell processes. There are close to 500 types of ...

Researchers have found out why the African naked mole-rat, one of the world's most unusual mammals, feels no pain when exposed to acid. The animals have an altered ion channel in their pain receptors ...

Human skin is constantly exposed to solar ultraviolet radiation (UVR), the most prevalent environmental carcinogen. Humans have the unique ability among mammals to respond to UVR by increasing their ...