DnaK/DnaJ or Trigger factor and find that chaperone dependence during primary biogenesis in vivo does not track with ...

Numerous BYU students, including Mikaila Sass (pictured), worked with Dr. Willardson in his lab on this discovery. The human body heavily relies on protein molecules for proper functioning. Protein ...

Heat shock proteins (HSPs) and molecular chaperones are fundamental to cellular proteostasis, ensuring proteins achieve and maintain their functional conformation while preventing misfolding and ...

J. Frydman, E. Nimmesgern, K. Ohtsuka, F.U. Hartl, "Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones," Nature, 370:111-7, 1994. (Cited in nearly 50 ...

Ribosomes are the cell's protein factories, which read the genetic code and assemble the proteins that every organism needs ...

An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin has introduced CGSchNet, a machine-learned coarse-grained (CG) model that can ...

While we often think of diseases as caused by foreign bodies -- bacteria or viruses -- there are hundreds of diseases affecting humans that result from errors in cellular production of its proteins. A ...

When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...

Penn Engineers have developed a mathematical "Rosetta Stone" that translates atomic and molecular movements into predictions ...

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This is a preview. Log in through your library . Abstract Epilepsy is a group of neurological diseases which requires significant economic costs for the treatment and care of patients. The central ...