Epigenetic regulation is mainly mediated by enzymes that can modify the structure of chromatin by altering the structure of DNA or histones. Proteins involved in epigenetic processes have been ...
A scientific team led by researchers at Trinity College Dublin reports the discovery of new mechanisms involved in establishing cellular identity, a process that ensures the billions of different ...
The key protein complex PRC2 was discovered decades ago to silence genes, but new findings by Frederic Berger and his group at the Gregor Mendel Institute show that PRC2 represses transposons in a ...
A team of scientists led by those in Trinity College Dublin has discovered new mechanisms involved in establishing cellular identity, a process that ensures the billions of different cells in our ...
The Polycomb group (PcG) protein Enhancer of Zeste Homolog 2 (EZH2) is one of the three core subunits of the Polycomb Repressive Complex 2 (PRC2). It harbors histone methyltransferase activity (MTase) ...
A team of scientists led by those in Trinity College Dublin has discovered new mechanisms involved in establishing cellular identity, a process that ensures the billions of different cells in our ...