Protein-degrader structure and function have been captured in unprecedented detail. Protein degraders are recognized as an exciting avenue for drug discovery and development, providing targeted ...
The polypyrimidine tract binding protein (PTB) binds pre-mRNAs to alter splice-site choice. We characterized a series of spliceosomal complexes that assemble on a pre-mRNA under conditions of either ...
Recently identified and long-lasting type of protein misfolding — non-native entanglements — observed in all-atom protein folding simulations. Representative misfolded conformations of the small ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 78, No. 12, [Part 2: Biological Sciences] (Dec., 1981), pp. 7820-7824 (5 pages) Tight junctions between cerebral ...
Arbiom is a start-up developing solutions to convert timber by-products into food and feed ingredients. The group recently unveiled its first protein ingredient, SylPro. We caught up with the company ...
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