The Mustangs jumped out to an early double-digit lead, but the Cardinals responded and rolled to a 14-point win.

Pat Kelsey's Louisville Cardinals turned their struggles vs Duke into strengths against SMU at the KFC Yum! Center. Louisville basketball is now 15-6.

There were some basketball pundits (and by “some,” I mean me) who said before this season that Louisville was likely to go as far as freshman

SMU Mustangs (15-5, 4-3 ACC) at Louisville Cardinals (14-6, 4-4 ACC) Louisville, Kentucky; Saturday, 2 p.m. EST BETMGM SPORTSBOOK LINE: Cardinals -7.5; over/under is 164.5 BOTTOM LINE: SMU visits No.

The Cardinals trailed by 12 in the first five minutes of the game, but battled back to deliver a strong second half against the Mustangs.

Louisville was forced to respond following a historic road loss at No. 4 Duke, and did it with an emphatic second half in an 88-74 win over SMU. Pat Kelsey’s team trailed by as many as 12 in the opening minutes,

Still with two months remaining before the NCAA Tournament, SMU is already through the most challenging part of its 2025-26 schedule. After facing three ranked opponents already this month, SMU has just two matchups left on its schedule against teams currently in the AP top 25 — a pair of games against No.

The No. 20 Louisville Cardinals host the SMU Mustangs Saturday afternoon for a 2 p.m. ET tip from KFC Yum! Center in Louisville, Kentucky.

After another great season in the ACC, SMU has the schedule to keep it going. Here's the CFN breakdown of the 2026 Mustang slate.

Also of note, three of SMU’s game dates are to be determined. California at SMU will take place on Oct. 23 or 24, SMU at Syracuse will take place on Oct. 30 or Oct. 31 and Virginia Tech at SMU will take place on Nov. 6 or Nov. 7.