A new review in Cell Regeneration explains why transient senescent cells support muscle repair while persistent senescence in ...

Skeletal muscles are capable of regenerating themselves following an injury, a process that depends on muscle stem cells. In healthy resting muscle, these cells are predominantly in a quiescent state.

Because RyR1 is also expressed in neurons, immune cells, and vascular smooth muscle, the E3896A model offers a unique tool to examine CICR's broader physiological roles. By combining gene engineering, ...

Skeletal muscles grow and regenerate as individual precursor cells—called myoblasts—fuse into long fibers from which mature muscle fibers develop. How they coordinate this process and form functional ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Space exploration activity has been increasing. In turn, researchers are more interested than ever in uncovering more about how space travel affects human health and the progression of disease.

A study of goat embryos identifies CDK1 as a hub gene whose moderate expression promotes muscle satellite cell proliferation, ...

When bones break and there is extreme tissue loss--such as after a car accident or a battlefield injury--current treatments don't often lead to effective healing. But certain stem cells from skeletal ...