A study in human prostate tissues finds that inhibitors of the Rab GTPases Rab7 and Rab27 fail to consistently alter ...

A research group has uncovered important details about how platelet-activating factor (PAF)—a powerful molecule involved in inflammation and allergic reactions—triggers contractions in the smooth ...

Salacia spp. is a plant material that has been studied primarily in the field of glucose metabolism, including its ...

Calcium ions orchestrate contraction and relaxation in airway smooth muscle by regulating excitation–contraction coupling. In quiescent cells, basal cytosolic Ca2+ is maintained at nanomolar levels by ...

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...

Different tissues need different amounts of blood depending on what they are doing. Meeting those changing demands requires the circulatory system to continually balance how much blood flows to ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

A research group has discovered that certain naturally occurring peptides in the body can trigger contractions in the vas deferens—a muscular tube that carries sperm in the male reproductive system.