SINCE the introduction of nitrogen mustard, methyl-bis-β-(chloroethyl)-amine, or HN 2 (Fig. 1), as a therapeutic agent in human cancer a number of analogues and related alkylating agents have been ...
Phase I, Pharmacokinetic, and Pharmacodynamic Study of Intravenously Administered Ad5CMV-p53, an Adenoviral Vector Containing the Wild-Type p53 Gene, in Patients With Advanced Cancer UFT+LV achieved ...
Samples from the asteroid Ryugu collected by the Hayabusa2 mission contain nitrogenous organic compounds, including the nucleobase uracil, which is a part of RNA. Samples from the asteroid Ryugu ...
In a previous phase 3 trial of adjuvant chemotherapy after resection of non–small-cell lung cancer, a combination of uracil and tegafur (often referred to as UFT) taken orally was shown to prolong ...
In a recent study published in PLOS Pathogens, researchers reviewed the existing knowledge on the mechanisms through which deoxyribonucleic acid (DNA) tumor viruses (DTVs) evade the antiviral immunity ...
Plasma concentrations of uracil (U) and its dihydrogenated metabolite, dihydrouracil (UH 2), were measured before treatment, and the ratio of UH 2 to U was calculated. Pharmacokinetic and ...