When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...
Randal Halfmann at the Stowers Institute for Medical Research in Kansas City is hoping to treat diseases including cancer and ...
Repeat proteins, defined by sequential arrays of short structural motifs, offer an intriguing departure from the folding behaviour of conventional globular proteins. Their modular architecture enables ...
A new study offers new insights into the evolution of foldable proteins. A new study led by Rice University's Peter Wolynes offers new insights into the evolution of foldable proteins. The research ...
In a human body, cells are constantly making life-or-death decisions. If they make the wrong choice, the result can be cancer. It may be possible to treat diseases by influencing this behavior. In the ...
A comprehensive analysis of over 500,000 human protein variants reveals that 60% of disease-causing missense mutations reduce protein stability In a recent study published in Nature, researchers used ...
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