With the opening line of Duke’s Sweet 16 hovering near double digits, the Blue Devils are heavily favored in their matchup against No. 4 Arizona. Displaying dominant two-way play through two games, it’s easy to see why Duke currently sits at No. 1 entering the second weekend.

Duke will be the team to beat in San Antonio, Texas, next week for the 2025 Final Four, according to betting lines that opened at the conclusion of the NCAA Tournament's second weekend on Sunday. The Blue Devils have the shortest odds at +105 to win the national championship ahead of Florida,

Just as they did in the 2024 NCAA Tournament, Duke and Houston will play in March Madness this season. This time it’s in the Final Four national semifinals at San Antonio.

The action in the 2025 NCAA Women’s Basketball Tournament kicks back up on Friday, March 28 in Regional 2 in Birmingham where bitter rivals the North Carolina Tar Heels and Duke Blue Devils meet for the third time this season, this time in the Sweet 16 at Legacy Arena at BJCC in Birmingham, Ala.

The stage is set for a potentially epic Elite Eight showdown as No. 1 seed Duke and No. 2 seed Alabama will face off Saturday with a spot in the Final Four on the line. Both teams reached 100 points in their Sweet 16 victories and are brimming with the high-end talent necessary to create a compelling March Madness showdown.

Catch all the NCAA Tournament action between the Duke Blue Devils and South Carolina Gamecocks in this Elite 8 March Madness matchup live on Sunday.